Chloromethane

Chloromethane

SCHEMBL28663449

C=C(C)C(=O)ON(C)C.CCl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 3/20 0.37
THRB P10828 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL545157 0.95
Methacrylic Acid SCHEMBL3224578 0.88 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1KDM6B
Acetic Acid SCHEMBL27717828 0.88 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1KDM6B
SCHEMBL28029837 0.86 ALDH1A1 (0.48) ALDH1A1TSHRTHRBTDP1KDM6B
SCHEMBL25410111 0.82 ALDH1A1 (0.42) ALDH1A1TSHRTHRBTDP1KDM6B
SCHEMBL11517514 0.77
SCHEMBL27773769 0.75 ALDH1A1 (0.35) ALDH1A1TDP1KDM6BKDM5CEGLN1
Chloromethane SCHEMBL27884873 0.75 ALDH1A1 (0.31) ALDH1A1KDM6BKDM5CEGLN1PHF8
Chloromethane SCHEMBL5491655 0.75 KDM6B (0.34) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL1401727 0.74 KDM6B (0.43) ALDH1A1TSHRKDM6BKDM5CEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117730109-A Artificial polymers with altered oligosaccharide or polysaccharide functionality or narrow oligosaccharide distribution, methods of making the same, compositions comprising the same, and methods of use thereof 诺力昂化学品国际有限公司 2024-03-19 CN disclosed
CN-107923838-B Biological material measuring instrument 泰斯科有限公司 2021-11-26 CN disclosed