Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664212 | 1.00 | CHRNB2 (0.55) | CHRNB2CHRNA4PRKCZ | |
| SCHEMBL19023247 | 0.91 | HRH1 (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL29483104 | 0.91 | HRH1 (0.49) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL19023121 | 0.90 | HRH1 (0.47) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL19023565 | 0.90 | HRH1 (0.47) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL28633579 | 0.88 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL28645846 | 0.88 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL31470955 | 0.88 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL19023342 | 0.83 | CHRNB2 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL19023299 | 0.83 | CHRNB2 (0.40) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-B | Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2021-12-14 | — | — | CN | disclosed |