Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664219 | 1.00 | GPR119 (0.57) | GPR119PIK3CDPIK3CAEPHX2 | |
| SCHEMBL2775708 | 0.93 | GPR119 (0.62) | GPR119EPHX2 | |
| SCHEMBL2997553 | 0.90 | GPR119 (0.52) | GPR119PIK3CDPIK3CAEPHX2 | |
| SCHEMBL26665862 | 0.82 | GPR119 (0.57) | GPR119PIK3CDPIK3CA | |
| SCHEMBL26665866 | 0.82 | GPR119 (0.57) | GPR119PIK3CDPIK3CA | |
| SCHEMBL26180089 | 0.82 | GPR119 (0.57) | GPR119PIK3CDPIK3CA | |
| SCHEMBL20179635 | 0.82 | GPR119 (0.57) | GPR119PIK3CDPIK3CA | |
| SCHEMBL29756681 | 0.82 | GPR119 (0.57) | GPR119PIK3CDPIK3CA | |
| SCHEMBL20137677 | 0.82 | EPHX2 (0.55) | EPHX2 | |
| SCHEMBL20137678 | 0.82 | EPHX2 (0.55) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-B | Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2021-12-14 | — | — | CN | disclosed |