SCHEMBL28664237

SCHEMBL28664237

Nc1ccc(Cl)cc1-n1cccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.53
IDO1 P14902 1/20 0.53
MAT2A P31153 2/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
G6PD P11413 1/20 0.46
TDO2 P48775 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.41
NPC1 O15118 1/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511117 0.79 ADRA1A (0.48) NOTUMALDH1A1MEN1KMT2AGAA
SCHEMBL30908194 0.79 ADRA1A (0.48) NOTUMALDH1A1MEN1KMT2AGAA
SCHEMBL11023550 0.79 NOTUM (0.56) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL30055522 0.79 NOTUM (0.56) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL15058948 0.76 NOTUM (0.53) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL30462819 0.76 NOTUM (0.53) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL30719692 0.76 NOTUM (0.53) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL1531523 0.76 MAPK1 (0.56) NOTUMMAT2AALDH1A1MEN1KMT2A
SCHEMBL25025064 0.76 KCNH2 (0.47) ALDH1A1MEN1KMT2AGAALMNA
SCHEMBL1196311 0.76 NOTUM (0.49) NOTUMMAT2AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851584-B Non-activated beta-C (sp) in the synthesis of carboxylic acid derivatives 3 ) Method for nitrating-H bond 南京理工大学 2022-11-25 CN claimed
CN-112851584-B Non-activated beta-C (sp) in the synthesis of carboxylic acid derivatives 3 ) Method for nitrating-H bond 南京理工大学 2022-11-25 CN disclosed
CN-112851584-A Nitric acid esterification method for non-activated beta-C (sp3) -H bond in synthesis of carboxylic acid derivative 南京理工大学 2021-05-28 CN disclosed