Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676277 | 0.98 | MAOB (0.65) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL13134181 | 0.84 | MAOB (0.49) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL29277424 | 0.83 | MAOB (0.67) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL292868 | 0.80 | MAOB (0.71) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL20378369 | 0.79 | MAOB (0.76) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL12655257 | 0.78 | MAOB (0.73) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL6557580 | 0.78 | MAOB (1.00) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL293779 | 0.77 | MAOB (0.67) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL9075843 | 0.76 | MAOB (0.71) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL8359747 | 0.76 | MAOB (0.71) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651788-B | 3-aminoalkylchromone compound and preparation method thereof | 东华理工大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-113651788-A | 3-amine alkyl chromone compound and preparation method thereof | 东华理工大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651788-A | 3-amine alkyl chromone compound and preparation method thereof | 东华理工大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651788-A | 3-amine alkyl chromone compound and preparation method thereof | 东华理工大学 | 2021-11-16 | — | — | CN | disclosed |