Formamide

Formamide

SCHEMBL28664418

Cc1c(C)n(S(=O)(=O)c2ccccc2)c2ncc([N+](=O)[O-])cc12.NC=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.46
AGTR1 P30556 1/20 0.39
POLB P06746 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.38
DCTPP1 Q9H773 1/20 0.38
NOD1 Q9Y239 2/20 0.38
AR P10275 1/20 0.38
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
NOD2 Q9HC29 1/20 0.35
MET P08581 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1772875 0.94 PTGDR2 (0.50) PTGDR2AGTR1POLBSMN1; SMN2MAPT
Formamide SCHEMBL28651025 0.77 PTGDR2 (0.60) PTGDR2
SCHEMBL1772632 0.76 ALDH1A1 (0.46) PTGDR2AGTR1POLBSMN1; SMN2MAPT
SCHEMBL2962255 0.76 PTGDR2 (0.46) PTGDR2LMNAGAA
SCHEMBL25811422 0.75 MAPT (0.57) PTGDR2POLBSMN1; SMN2MAPTDCTPP1
SCHEMBL1772606 0.74 BRD4 (0.44) PTGDR2AGTR1POLBSMN1; SMN2MAPT
SCHEMBL1772584 0.73 ALDH1A1 (0.43) PTGDR2AGTR1POLBSMN1; SMN2MAPT
SCHEMBL1773798 0.71 ALDH1A1 (0.45) PTGDR2AGTR1POLBSMN1; SMN2DCTPP1
SCHEMBL1771967 0.70 KMT2A (0.44) PTGDR2AGTR1POLBSMN1; SMN2MAPT
SCHEMBL1773016 0.70 PTGDR2 (0.67) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113727972-A Novel hydrazone derivatives in which terminal amino group is substituted with aryl or heteroaryl group, and use thereof 韩国科学技术研究院 2021-11-30 CN disclosed