SCHEMBL28664446

SCHEMBL28664446

C=CCc1cccc(O)c1C(=O)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PTPN1 P18031 1/20 0.43
NSD2 O96028 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
EP300 Q09472 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
MAPT P10636 3/20 0.39
PTK2B Q14289 1/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12921072 0.82 HPGD (0.53) HPGDALOX15HSD17B10PTPN1NSD2
SCHEMBL11766953 0.81 HSD17B10 (0.68) HPGDALOX15HSD17B10NSD2MAPT
SCHEMBL3803126 0.80 KAT8 (0.56) ALOX15HSD17B10GABRA1GABRB2EP300
SCHEMBL4603952 0.79 CYP3A4 (0.50) HSD17B10GABRA1GABRB2EP300KAT2B
SCHEMBL30083988 0.79 HSD17B10 (0.53) HPGDALOX15HSD17B10PTPN1NSD2
SCHEMBL13714211 0.79 HSD17B10 (0.53) HPGDALOX15HSD17B10PTPN1NSD2
SCHEMBL680146 0.78 GABRA1 (0.52) HSD17B10GABRA1GABRB2EP300KAT2B
SCHEMBL1570712 0.77 GABRA1 (0.47) HSD17B10GABRA1GABRB2EP300KAT2B
SCHEMBL10893913 0.77 MAPT (0.49) HPGDALOX15HSD17B10PTPN1GABRA1
SCHEMBL31429734 0.77 GABRA1 (0.50) HSD17B10GABRA1GABRB2EP300KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113802370-B Composite wear-resistant fabric 江苏三盛纺织有限公司 2022-04-29 CN disclosed
CN-113802370-A Composite wear-resistant fabric 江苏三盛纺织有限公司 2021-12-17 CN disclosed