Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690167 | 0.86 | MAPT (0.38) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL5118526 | 0.80 | MAPT (0.38) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL19047476 | 0.77 | MAPK14 (0.39) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL28756320 | 0.77 | MAPK14 (0.37) | MAPTSMN1; SMN2TP53SRCSYK | |
| Hydrochloric Acid SCHEMBL7795325 | 0.76 | RARG (0.35) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL19047477 | 0.75 | MAPT (0.36) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL28942237 | 0.75 | CA1 (0.38) | MAPTSMN1; SMN2TP53ALDH1A1PDE3B | |
| SCHEMBL690623 | 0.74 | RARG (0.41) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL28756194 | 0.74 | GSK3A (0.39) | SRCSYKGSK3AMAPK14 | |
| SCHEMBL28650716 | 0.74 | MAPT (0.33) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071505-B | Kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-16 | — | — | CN | disclosed |