Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 16/20 | 0.39 |
| ▸ | SRC | P12931 | 14/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.39 |
| ▸ | SYK | P43405 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756114 | 0.83 | GSK3A (0.39) | GSK3ASRCMAPK14SYK | |
| SCHEMBL28756081 | 0.82 | SRC (0.40) | GSK3ASRCMAPK14SYK | |
| SCHEMBL16829546 | 0.81 | GSK3A (0.40) | GSK3ASRCMAPK14SYK | |
| SCHEMBL28756124 | 0.78 | MEN1 (0.38) | GSK3ASRCMAPK14SYK | |
| SCHEMBL19434654 | 0.77 | ALDH1A1 (0.36) | MAPK14 | |
| SCHEMBL28942237 | 0.76 | CA1 (0.38) | GSK3AMAPK14 | |
| SCHEMBL16829471 | 0.76 | GSK3A (0.49) | GSK3ASRCMAPK14SYK | |
| SCHEMBL16829308 | 0.76 | ALDH1A1 (0.44) | GSK3ASRCMAPK14SYK | |
| SCHEMBL28650716 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL28756320 | 0.75 | MAPK14 (0.37) | GSK3ASRCMAPK14SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717162-A | Urea derivatives as kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-30 | — | — | CN | disclosed |