Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.45 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | PYGM | P11217 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842510 | 1.00 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9862851 | 1.00 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL1842511 | 1.00 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL4602205 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL4224352 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7074366 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7074369 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL10408121 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7107462 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL824879 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218231-B | Cyclobutane dicarboxylic acid platinum complex, intermediate thereof, preparation method thereof, pharmaceutical composition and application thereof | 天津谷堆生物医药科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114096268-A | Methods for increasing growth in pediatric subjects with cholestatic liver disease | 米鲁姆制药公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114072152-A | Genotype and dose-dependent response to ASBTI in patients with bile salt efflux pump deficiency | 米鲁姆制药公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072153-A | Methods for treating cholestasis | 米鲁姆制药公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-106573957-B | Derivatives from hyaluronic acid and carnosine | 塞巴斯蒂安诺·舒托 | 2021-10-26 | — | — | CN | disclosed |