Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 12/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | PDE8B | O95263 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 2/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014455 | 0.84 | KMT2A (0.54) | NPBWR1MCHR1F2KMT2APKM | |
| SCHEMBL25345977 | 0.84 | NPBWR1 (0.55) | NPBWR1MCHR1PKMPKLRKDM4E | |
| SCHEMBL4679664 | 0.82 | NPBWR1 (0.61) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL28669329 | 0.81 | NPBWR1 (0.60) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL3356641 | 0.80 | NPBWR1 (0.49) | NPBWR1MCHR1F2KMT2APKM | |
| SCHEMBL4680318 | 0.79 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL27176044 | 0.79 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL24640867 | 0.79 | NPBWR1 (0.68) | NPBWR1MCHR1PKMPKLRALDH1A1 | |
| SCHEMBL30685695 | 0.78 | NPBWR1 (0.56) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL30515984 | 0.75 | PDE8B (0.46) | NPBWR1MCHR1F2KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |