SCHEMBL28664823

SCHEMBL28664823

CC=CCC1=C(C)C(=O)C(C)=CC1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.33
MEN1 O00255 2/20 0.33
USP2 O75604 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
PLIN1 O60240 1/20 0.33
NR1I2 O75469 1/20 0.33
GSR P00390 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CYP2D6 P10635 1/20 0.33
HSPD1 P10809 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24071118 1.00 MAOB (0.33) MAOBMEN1USP2ALDH1A1GAA
SCHEMBL9027595 0.79 MEN1 (0.34) MAOBMEN1USP2ALDH1A1GAA
SCHEMBL24071088 0.77 MAPT (0.39) MAOBMEN1USP2ALDH1A1GAA
SCHEMBL24071110 0.76 MAOB (0.46) MAOBMEN1ALDH1A1MAPTMAPK1
SCHEMBL24071117 0.76 ALDH1A1 (0.38) MAOBMEN1USP2ALDH1A1GAA
SCHEMBL24071111 0.72 MAOB (0.68) MAOBMAPTMAPK1LMNAADORA3
SCHEMBL28910464 0.71 MAOB (0.68) MAOBMAPTMAPK1LMNAADORA3
SCHEMBL1785127 0.70 IDO1 (0.33) MAOBMEN1USP2ALDH1A1GAA
SCHEMBL12921592 0.69 MAPT (0.55) ALDH1A1MAPTMAPK1LMNAADORA3
SCHEMBL17029396 0.69 MAPT (0.55) ALDH1A1MAPTMAPK1LMNAADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115697956-A Preparation method of quinone compound 上海科技大学 2023-02-03 CN disclosed
CN-113735696-B Preparation method of quinone compound 上海科技大学 2022-11-08 CN disclosed
CN-113735696-A Preparation method of quinone compound 上海科技大学 2021-12-03 CN disclosed