SCHEMBL28664873

SCHEMBL28664873

CC[C@H](C)[C@H](NC=O)C(=O)O.[KH]

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.45
FPR2 P25090 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
CA2 P00918 2/20 0.38
MME P08473 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
CA1 P00915 1/20 0.38
ENPEP Q07075 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2377592 0.98 ALDH1A1 (0.53) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL2377589 0.98 ALDH1A1 (0.53) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL9825702 0.98 ALDH1A1 (0.53) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL28671686 0.96 ALDH1A1 (0.52) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL28663225 0.96 ALDH1A1 (0.52) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL27976190 0.96 ALDH1A1 (0.52) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL16623912 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL18098723 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL16623919 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1FPR2MEN1KMT2A
SCHEMBL16623913 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1FPR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735727-A Preparation method of racemic ketone isoleucine calcium and intermediate thereof 北京福元医药股份有限公司沧州分公司 2021-12-03 CN disclosed