Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702119 | 0.82 | NPC1 (0.59) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2844247 | 0.82 | NPC1 (0.59) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1104644 | 0.76 | KMT2A (0.53) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20913321 | 0.74 | KDM4E (0.48) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1950236 | 0.73 | KMT2A (0.64) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4897079 | 0.73 | KMT2A (0.64) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL221242 | 0.73 | KMT2A (0.76) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29391624 | 0.73 | KMT2A (0.76) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15679551 | 0.73 | KMT2A (0.53) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22970594 | 0.72 | HTT (0.58) | HTTCYP1A2CYP2C19KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | disclosed |