Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL29751902 | 1.00 | MAPT (0.32) | MAPTMEN1ALDH1A1LMNATHRB | |
| SCHEMBL3303342 | 0.98 | MEN1 (0.30) | MEN1LMNAHTTKMT2A | |
| SCHEMBL29886999 | 0.98 | MEN1 (0.30) | MEN1LMNAHTTKMT2A | |
| Bromide SCHEMBL30881515 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL31674658 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL3963006 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL3963721 | 0.94 | — | — | |
| Iodide SCHEMBL28456520 | 0.71 | APP (0.35) | MAPTMEN1KMT2AAPP | |
| SCHEMBL19730859 | 0.71 | SIGMAR1 (0.31) | — | |
| SCHEMBL30532134 | 0.71 | SIGMAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078716-B | Fluorescent probe for detecting glutathione and preparation method and application thereof | 华南理工大学 | 2021-11-23 | — | — | CN | claimed |
| CN-110078716-B | Fluorescent probe for detecting glutathione and preparation method and application thereof | 华南理工大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-110078716-B | Fluorescent probe for detecting glutathione and preparation method and application thereof | 华南理工大学 | 2021-11-23 | — | — | CN | disclosed |