SCHEMBL28665367

SCHEMBL28665367

COc1cc(CC2COC(O)C2Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 0.74
SHBG P04278 3/20 0.67
CYP2D6 P10635 3/20 0.63
GAA P10253 2/20 0.58
POLB P06746 1/20 0.58
PKM P14618 1/20 0.58
APEX1 P27695 1/20 0.58
RECQL P46063 1/20 0.58
BLM P54132 1/20 0.58
SLC6A3 Q01959 1/20 0.55
MAPK1 P28482 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
MAP2K1 Q02750 1/20 0.55
NDUFS8 O00217 1/20 0.53
COXFA4 O00483 1/20 0.53
NDUFAB1 O14561 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18677719 1.00 CYP3A4 (0.74) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL29477287 0.85 CYP3A4 (1.00) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL30098864 0.80 SHBG (1.00) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL30217506 0.80 SHBG (1.00) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL3470642 0.80 SHBG (1.00) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL13557926 0.80 CYP3A4 (0.62) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL29583327 0.80 CYP3A4 (0.86) CYP3A4CYP2D6SLC6A3NPC1RAB9A
SCHEMBL13322127 0.80 CYP3A4 (0.62) CYP3A4SHBGCYP2D6GAAPOLB
SCHEMBL13979662 0.80 CYP3A4 (0.86) CYP3A4CYP2D6SLC6A3NPC1RAB9A
SCHEMBL30123810 0.80 CYP3A4 (0.62) CYP3A4SHBGCYP2D6GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107802676-B Lilac extract and preparation method and application thereof 甘肃奇正藏药有限公司 2021-07-06 CN claimed
CN-107802674-B Lilac extract and preparation method and application thereof 甘肃奇正藏药有限公司 2021-07-06 CN claimed
CN-107802676-B Lilac extract and preparation method and application thereof 甘肃奇正藏药有限公司 2021-07-06 CN disclosed
CN-107802674-B Lilac extract and preparation method and application thereof 甘肃奇正藏药有限公司 2021-07-06 CN disclosed
CN-107802674-B Lilac extract and preparation method and application thereof 甘肃奇正藏药有限公司 2021-07-06 CN disclosed