SCHEMBL28665402

SCHEMBL28665402

COc1ccc(NC(=O)c2ccccc2Nc2cccc(C(F)(F)F)c2)cc1OC

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 16/20 0.80
PTGS2 P35354 2/20 0.63
TOP1 P11387 1/20 0.63
NR1H4 Q96RI1 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28681441 0.90 RXFP1 (0.75) RXFP1TOP1
SCHEMBL15529016 0.89 RXFP1 (1.00) RXFP1
SCHEMBL15528884 0.89 RXFP1 (1.00) RXFP1
SCHEMBL28670788 0.88 RXFP1 (0.76) RXFP1
SCHEMBL15528928 0.85 RXFP1 (1.00) RXFP1
SCHEMBL15529210 0.85 RXFP1 (1.00) RXFP1
SCHEMBL30927042 0.84 MEN1 (0.64) RXFP1PTGS2TOP1NR1H4
SCHEMBL27179805 0.84 MEN1 (0.64) RXFP1PTGS2TOP1NR1H4
SCHEMBL5491795 0.84 RXFP1 (0.88) RXFP1
SCHEMBL15528909 0.83 RXFP1 (1.00) RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651768-A N-aryl anthranilamide compound and preparation and application thereof 南华大学 2021-11-16 CN disclosed