Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.63 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.54 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.54 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | USP8 | P40818 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179805 | 1.00 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPK1SLC20A2 | |
| SCHEMBL23200355 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SLC20A2SLC20A1 | |
| SCHEMBL30926890 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SLC20A2SLC20A1 | |
| SCHEMBL30926577 | 0.85 | MEN1 (0.76) | MEN1KMT2ASLC20A2SLC20A1RXFP1 | |
| SCHEMBL7128448 | 0.85 | MEN1 (0.76) | MEN1KMT2ASLC20A2SLC20A1RXFP1 | |
| SCHEMBL28665402 | 0.84 | RXFP1 (0.80) | RXFP1NR1H4TOP1PTGS2 | |
| SCHEMBL30926819 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPK1SLC20A2 | |
| SCHEMBL27181165 | 0.84 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPK1SLC20A2 | |
| SCHEMBL28454669 | 0.83 | MEN1 (0.64) | MEN1KMT2ASLC20A2SLC20A1RXFP1 | |
| SCHEMBL7120286 | 0.83 | SLC20A2 (0.74) | MEN1KMT2AALDH1A1SLC20A2SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885ALDH1A1 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.