Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15485406 | 0.85 | KMT2A (0.48) | KMT2ASMN1; SMN2GAAMEN1HSD17B10 | |
| SCHEMBL28688165 | 0.85 | PARP1 (0.45) | KMT2ASMN1; SMN2GAAMEN1HSD17B10 | |
| SCHEMBL20956786 | 0.81 | HRH3 (0.48) | HSD17B10ALDH1A1CA12CA9MAPK1 | |
| SCHEMBL5430075 | 0.81 | HRH3 (0.48) | HSD17B10ALDH1A1CA12CA9MAPK1 | |
| SCHEMBL23119906 | 0.78 | CA12 (0.43) | KMT2AMEN1ALDH1A1CA12CA9 | |
| SCHEMBL20956682 | 0.78 | CA12 (0.43) | KMT2AMEN1ALDH1A1CA12CA9 | |
| SCHEMBL21551126 | 0.77 | KEAP1 (0.47) | CA12CA9KEAP1 | |
| SCHEMBL23910438 | 0.77 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL20479505 | 0.77 | PARP1 (0.46) | KMT2A | |
| SCHEMBL17068112 | 0.77 | PARP1 (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-B | 3-tetrazolyl-benzene-1, 2-disulfonamide derivatives as metallo-beta-lactamase inhibitors | 默沙东公司 | 2021-07-13 | — | — | CN | disclosed |