Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054295 | 0.98 | TSHR (0.55) | TSHRCYP3A4MAPK1TP53MMP8 | |
| SCHEMBL14680133 | 0.98 | TSHR (0.55) | TSHRCYP3A4MAPK1TP53MMP8 | |
| SCHEMBL14680117 | 0.98 | TSHR (0.55) | TSHRCYP3A4MAPK1TP53MMP8 | |
| SCHEMBL16732085 | 0.95 | TSHR (0.55) | TSHRCYP3A4MAPK1TP53MMP8 | |
| SCHEMBL14199944 | 0.88 | MMP8 (0.58) | TP53MMP8ALDH1A1LMNATDP1 | |
| SCHEMBL28343537 | 0.87 | TSHR (0.54) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL5668365 | 0.86 | TSHR (0.53) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL17077436 | 0.84 | ALPI (0.53) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL27549297 | 0.84 | TSHR (0.54) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL299866 | 0.84 | ALPI (0.53) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678997-B | Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | disclosed |