SCHEMBL2866599

SCHEMBL2866599

C=Cn1ccnc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ESR1 P03372 1/20 0.42
HCRTR1 O43613 1/20 0.41
USP2 O75604 1/20 0.41
MAPK1 P28482 1/20 0.41
KDR P35968 7/20 0.38
CHEK1 O14757 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
LIMK1 P53667 1/20 0.38
MAPK14 Q16539 1/20 0.38
MAP4K4 O95819 1/20 0.37
CSF1R P07333 1/20 0.37
PRKACA P17612 1/20 0.37
CDK8 P49336 1/20 0.37
MAP2K1 Q02750 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10392069 0.85 CYP11B1 (0.40) GAASMN1; SMN2LMNATDP1ALDH1A1
SCHEMBL14921747 0.85 ESR1 (0.42) GAASMN1; SMN2TDP1ESR1KDR
SCHEMBL27816158 0.83 LMNA (0.46) GAASMN1; SMN2LMNATDP1HCRTR1
SCHEMBL10392070 0.83 CHEK1 (0.39) GAASMN1; SMN2LMNATDP1ESR1
SCHEMBL28145742 0.83 PDE4B (0.39) GAASMN1; SMN2LMNAESR1HCRTR1
SCHEMBL12468216 0.81 ESR1 (0.46) GAASMN1; SMN2TDP1ESR1KDR
SCHEMBL10782643 0.78 ESR1 (0.41) GAASMN1; SMN2TDP1ESR1KDR
SCHEMBL10782654 0.78 ESR1 (0.41) GAASMN1; SMN2TDP1ESR1KDR
SCHEMBL27551098 0.78 NPC1 (0.46) GAASMN1; SMN2LMNATDP1HCRTR1
SCHEMBL198066 0.76 SMN1; SMN2 (0.42) GAASMN1; SMN2LMNATDP1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9580591-B2 Use of hybrid copolymers as protective colloids for polymers WACKER CHEMIE AG (DE) 2017-02-28 US claimed
US-9522986-B2 Mineral construction material based on polyvinyl-alcohol-stabilized polymerisates WACKER CHEMIE AG (DE) 2016-12-20 US claimed
CN-104870395-B Use of hybrid copolymers as protective colloids for polymers 瓦克化学股份公司 2016-11-23 CN claimed
EP-2935142-B1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2016-10-12 EP claimed
CN-104870494-B The purposes of the stable polymerisate of polyvinyl alcohol in mineral construction thing material WACKER CHEMIE AG (DE) 2016-06-01 CN claimed
EP-2935357-B1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2016-05-11 EP claimed
US-20150315374-A1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2015-11-05 US claimed
US-20150307684-A1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2015-10-29 US claimed
CN-104870494-A Use of polyvinyl-alcohol-stabilised polymerisates in mineral construction materials WACKER CHEMIE AG 2015-08-26 CN claimed
EP-1761587-B1 PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER EVONIK ROEHM GMBH (DE) 2010-01-20 EP claimed
US-4933378-A Fluid loss control additives for oil well cementing compositions BASF CORPORATION (US) 1990-06-12 US claimed
US-4931489-A ACRYLAMIDE-VINYL IMIDAZOLE COPOLYMERS AND TERPOLYMERS MIXED WITH WATER AND HYDRAULIC CEMENT BASF CORPORATION (US) 1990-06-05 US claimed
EP-0342500-A2 Fluid loss control additives for oil well cementing compositions BASF Corporation (US) 1989-11-23 EP claimed
JP-56113291-A None JP disclosed
WO-2025004491-A1 PIGMENT DISPERSION, AQUEOUS COATING COMPOSITION, AND METHOD FOR PRODUCING SAME 日本ペイント・オートモーティブコーティングス株式会社 2025-01-02 WO disclosed
CN-114436967-B N-vinylation method of alkyl imidazole compound 博爱新开源制药有限公司 2024-01-26 CN disclosed
US-4133687-A Photographic elements having hydrophilic colloid layers containing compounds having activator precursors and hydrophobic developing agents uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1979-01-09 US disclosed
US-4115124-A WITH POLYVINYLIMIDAZOLE EASTMAN KODAK COMPANY (US) 1978-09-19 US disclosed
US-4082551-A GOOD ADHESION AND BLOCKING POSITIVE CHARGED PARTICLES EASTMAN KODAK COMPANY (US) 1978-04-04 US disclosed
US-3939132-A Process for the preparation of random copolymers of mono-olefins or of mono-olefins and unconjugated dienes with unsaturated derivatives selected from N-vinylimidazoles and N-vinylimidazolines SOCIETE NATIONALE DES PETROLES D'AQUITAINE (FR) 1976-02-17 US disclosed