Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666814 | 1.00 | GPR119 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19023504 | 0.93 | GPR119 (0.59) | GPR119PIK3CDALDH1A1 | |
| SCHEMBL29419894 | 0.93 | GPR119 (0.59) | GPR119PIK3CDALDH1A1 | |
| SCHEMBL31470957 | 0.91 | GPR119 (0.48) | GPR119PIK3CDPIK3CAUSP30ALDH1A1 | |
| SCHEMBL28638431 | 0.91 | GPR119 (0.48) | GPR119PIK3CDPIK3CAUSP30ALDH1A1 | |
| SCHEMBL28427023 | 0.88 | USP30 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31044606 | 0.88 | USP30 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28418675 | 0.88 | USP30 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31044644 | 0.88 | USP30 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28418678 | 0.88 | USP30 (0.52) | GPR119PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-B | Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2021-12-14 | — | — | CN | disclosed |