Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.54 |
| ▸ | VHL | P40337 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649816 | 0.89 | AR (0.56) | ARVHLALDH1A1NPC1RAB9A | |
| SCHEMBL30617809 | 0.88 | AR (0.57) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL30908029 | 0.88 | AR (0.57) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL28654521 | 0.88 | AR (0.56) | ARVHLALDH1A1NPC1RAB9A | |
| SCHEMBL28650197 | 0.88 | AR (0.58) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL23846235 | 0.87 | AR (0.61) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL22263332 | 0.87 | AR (0.60) | ARVHLRAF1BRAFALDH1A1 | |
| Hydrochloric Acid SCHEMBL30938119 | 0.86 | AR (0.59) | ARVHLALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL22263225 | 0.86 | AR (0.59) | ARVHLALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30938120 | 0.86 | AR (0.59) | ARVHLALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677668-A | Bifunctional compounds and methods for androgen receptor targeted ubiquitination | 蒙特利诺治疗公司 | 2021-11-19 | — | — | CN | disclosed |