SCHEMBL30908029

SCHEMBL30908029

CC(C)(C)OC(=O)NCCCCCCCCNC(=O)COc1c(-c2csc(N3CCOCC3)n2)ccc(F)c1F

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 13/20 0.57
▸ VHL P40337 1/20 0.53
▸ BRD4 O60885 1/20 0.39
▸ RAF1 P04049 1/20 0.39
▸ BRAF P15056 1/20 0.39
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ MERTK Q12866 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617809 1.00 AR (0.57) ARVHLBRD4RAF1BRAF
SCHEMBL28650197 0.99 AR (0.58) ARVHLBRD4RAF1BRAF
SCHEMBL25942687 0.92 AR (0.60) ARVHLRAF1BRAFNPC1
SCHEMBL30219486 0.92 AR (0.61) ARVHLBRD4RAF1BRAF
SCHEMBL26464151 0.92 AR (0.61) ARVHLBRD4RAF1BRAF
SCHEMBL23846235 0.90 AR (0.61) ARVHLRAF1BRAFNPC1
SCHEMBL22263332 0.89 AR (0.60) ARVHLRAF1BRAFNPC1
SCHEMBL28667525 0.88 AR (0.54) ARVHLRAF1BRAFNPC1
Hydrochloric Acid SCHEMBL30938120 0.88 AR (0.59) ARVHLNPC1RAB9ALMNA
Hydrochloric Acid SCHEMBL22263225 0.88 AR (0.59) ARVHLNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2024-06-27 — — US disclosed
WO-2024102810-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR MONTELINO THERAPEUTICS, INC. (US) 2024-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 AR 1/4885VHL 525/4885BRD4 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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