Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28681008 | 0.83 | PDGFRB (0.54) | PDGFRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL3746537 | 0.81 | PDGFRB (0.56) | PDGFRBALDH1A1LMNATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL28692453 | 0.80 | PDGFRB (0.54) | PDGFRBALDH1A1LMNATSHRMEN1 | |
| Bromide SCHEMBL10607715 | 0.68 | PDGFRB (0.39) | PDGFRBALDH1A1DRD2TSHRMEN1 | |
| SCHEMBL28903570 | 0.68 | ALDH1A1 (0.38) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL18844475 | 0.68 | BRD4 (0.53) | BRD4LMNAEHMT2 | |
| SCHEMBL28979322 | 0.67 | BRD4 (0.50) | BRD4EHMT2MEN1KMT2AHDAC1 | |
| SCHEMBL28138899 | 0.67 | BRD4 (0.40) | BRD4ALDH1A1LMNANPSR1EHMT2 | |
| SCHEMBL30541821 | 0.67 | PDGFRB (0.73) | PDGFRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL29403090 | 0.65 | PDGFRB (0.64) | PDGFRBALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912843-B | Porous metalloporphyrin polymer containing benzimidazole ionic liquid, and preparation method and application thereof | 广东石油化工学院 | 2023-07-07 | — | — | CN | disclosed |
| CN-113912843-A | Porous metalloporphyrin polymer containing benzimidazole ionic liquid and preparation method and application thereof | 广东石油化工学院 | 2022-01-11 | — | — | CN | disclosed |