Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CPT1A | P50416 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592889 | 0.91 | NR4A2 (0.77) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL17429435 | 0.84 | HTT (0.67) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL2866771 | 0.83 | NR4A2 (0.74) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL31451717 | 0.83 | NR4A2 (0.74) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL2053494 | 0.83 | HTT (0.70) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL27908679 | 0.82 | NR4A2 (0.77) | KMT2ALMNAMEN1MAPTMITF | |
| Hydrochloric Acid SCHEMBL7514852 | 0.82 | HTT (0.68) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL1558974 | 0.81 | NR4A2 (0.71) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL13727294 | 0.81 | LMNA (0.64) | KMT2ALMNAMEN1MAPTMITF | |
| SCHEMBL2834218 | 0.81 | NR4A2 (0.75) | KMT2ALMNAMEN1MAPTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213660-A1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | Obschestvo S Ogranichennoy Otvetstvennostju "Binatekh" (RU) | 2010-08-04 | — | — | EP | claimed |