Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.83 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.83 |
| ▸ | MAOA | P21397 | 2/20 | 0.83 |
| ▸ | MAOB | P27338 | 2/20 | 0.83 |
| ▸ | APP | P05067 | 10/20 | 0.78 |
| ▸ | MAPT | P10636 | 9/20 | 0.78 |
| ▸ | BACE1 | P56817 | 6/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.78 |
| ▸ | MMP9 | P14780 | 3/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.78 |
| ▸ | STAT3 | P40763 | 2/20 | 0.78 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.78 |
| ▸ | RELA | Q04206 | 2/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.78 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL28278390 | 0.92 | ABCB1 (0.97) | ABCB1AKR1B1MAOAMAOBAPP | |
| Curcumin SCHEMBL2837294 | 0.91 | APP (0.83) | ABCB1AKR1B1MAOAMAOBAPP | |
| Curcumin SCHEMBL27712095 | 0.91 | APP (0.83) | ABCB1AKR1B1MAOAMAOBAPP | |
| SCHEMBL2553051 | 0.91 | ABCB1 (1.00) | ABCB1AKR1B1MAOAMAOBAPP | |
| SCHEMBL431246 | 0.91 | ABCB1 (1.00) | ABCB1AKR1B1MAOAMAOBAPP | |
| SCHEMBL13521973 | 0.91 | ABCB1 (1.00) | ABCB1AKR1B1MAOAMAOBAPP | |
| SCHEMBL21327853 | 0.91 | ABCB1 (1.00) | ABCB1AKR1B1MAOAMAOBAPP | |
| Ferulate SCHEMBL972445 | 0.90 | SNCA (0.79) | ABCB1AKR1B1MAOAMAOBAPP | |
| Ferulate SCHEMBL29268602 | 0.90 | SNCA (0.79) | ABCB1AKR1B1MAOAMAOBAPP | |
| Curcumin SCHEMBL27887925 | 0.88 | APP (0.87) | ABCB1AKR1B1MAOAMAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109432055-B | Composite nano-particles of curcumin eutectic/piperine coated by polymer, preparation thereof and application thereof in sustained-release pharmaceutical preparation | 湖南湘源美东医药科技有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-109432055-B | Composite nano-particles of curcumin eutectic/piperine coated by polymer, preparation thereof and application thereof in sustained-release pharmaceutical preparation | 湖南湘源美东医药科技有限公司 | 2021-11-23 | — | — | CN | disclosed |