Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288369 | 1.00 | KMT2A (0.65) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL31611890 | 0.81 | MAPK1 (0.49) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL9841027 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL25042599 | 0.81 | MAPT (0.49) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL30275186 | 0.81 | MAPT (0.49) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL11158154 | 0.80 | ALDH1A1 (0.60) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL13767769 | 0.80 | ALDH1A1 (0.60) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL6819221 | 0.79 | POLB (0.68) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL1531344 | 0.79 | POLB (0.68) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL22714337 | 0.79 | HTT (0.61) | KMT2AALDH1A1MAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666882-B | Water phase preparation method of isoxazoline compound with participation of vitamin E micro-micelle | 浙江工业大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-113582937-B | Green preparation method of isoxazole compound participated in by water-soluble vitamin E | 浙江工业大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-113666882-A | Aqueous phase preparation method of isoxazoline compound participated by vitamin E micelle | 浙江工业大学 | 2021-11-19 | — | — | CN | disclosed |