Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668186 | 1.00 | DPP4 (0.36) | DPP4DPP7DPP8DPP9PDE4B | |
| SCHEMBL18205130 | 0.76 | HDAC4 (0.35) | DPP4DPP7PDE4BHDAC4FAP | |
| SCHEMBL28664389 | 0.75 | HDAC4 (0.42) | HDAC4 | |
| SCHEMBL28664388 | 0.75 | HDAC4 (0.42) | HDAC4 | |
| SCHEMBL19874797 | 0.75 | TAAR1 (0.33) | DPP4DPP7HDAC4 | |
| SCHEMBL28614556 | 0.75 | L3MBTL1 (0.43) | DPP4DPP7 | |
| SCHEMBL28614554 | 0.75 | L3MBTL1 (0.43) | DPP4DPP7 | |
| SCHEMBL18013067 | 0.74 | HDAC4 (0.31) | DPP4DPP7HDAC4 | |
| SCHEMBL19888514 | 0.73 | HDAC4 (0.34) | DPP4DPP7HDAC4 | |
| SCHEMBL28192982 | 0.73 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |