SCHEMBL28668397

SCHEMBL28668397

Nc1ccc2nc(-c3ccccc3O)[nH]c2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.67
F10 P00742 1/20 0.67
PLG P00747 1/20 0.67
PLAU P00749 1/20 0.67
PLAT P00750 1/20 0.67
HPN P05981 1/20 0.67
PRSS1 P07477 1/20 0.67
PRSS2 P07478 1/20 0.67
PRSS3 P35030 1/20 0.67
GAA P10253 10/20 0.63
MAPT P10636 10/20 0.63
KDM4E B2RXH2 8/20 0.63
SMN1; SMN2 Q16637 8/20 0.63
ALDH1A1 P00352 8/20 0.63
NPC1 O15118 7/20 0.63
RAB9A P51151 7/20 0.63
HPGD P15428 7/20 0.63
GLA P06280 4/20 0.63
HTT P42858 3/20 0.63
GFER P55789 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2245639 0.89 F2 (0.57) F2F10PLGPLAUPLAT
SCHEMBL20485660 0.89 MEN1 (0.65) F2F10PLGPLAUPLAT
SCHEMBL13973762 0.89 GAA (0.73) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL20485592 0.88 MEN1 (0.63) F2F10PLGPLAUPLAT
SCHEMBL11284879 0.84 GAA (0.73) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL29769324 0.83 ALDH1A1 (0.59) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL27914039 0.83 ALDH1A1 (0.59) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL13221240 0.82 GAA (0.77) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL3194047 0.82 ALDH1A1 (0.67) GAAMAPTKDM4ESMN1; SMN2ALDH1A1
SCHEMBL29946404 0.82 ADORA2A (0.65) F2F10PLGPLAUPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113698353-B Imidazolyl Schiff base fluorescence sensor for detecting copper (II) particles in aqueous solution and synthesis method thereof 桂林理工大学 2023-05-05 CN claimed
CN-113698353-A Imidazolyl Schiff base fluorescence sensor for detecting copper (II) particles in aqueous solution and synthetic method thereof 桂林理工大学 2021-11-26 CN claimed
CN-113698353-B Imidazolyl Schiff base fluorescence sensor for detecting copper (II) particles in aqueous solution and synthesis method thereof 桂林理工大学 2023-05-05 CN disclosed
CN-113698353-A Imidazolyl Schiff base fluorescence sensor for detecting copper (II) particles in aqueous solution and synthetic method thereof 桂林理工大学 2021-11-26 CN disclosed