Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 5/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.35 |
| ▸ | MYLK4 | Q86YV6 | 4/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16046180 | 0.81 | AKT2 (0.71) | AKT2AKT1ROCK1MYLK4HTR2A | |
| SCHEMBL1666064 | 0.77 | HTR2A (0.52) | HTR2ATAAR1HRH1 | |
| SCHEMBL2375241 | 0.76 | AKT2 (0.48) | AKT2AKT1ROCK1MYLK4ROCK2 | |
| SCHEMBL27975965 | 0.76 | AKT2 (0.44) | AKT2AKT1ROCK1ROCK2 | |
| SCHEMBL17875272 | 0.73 | AKT2 (0.47) | AKT2AKT1ROCK1MYLK4ROCK2 | |
| SCHEMBL16156937 | 0.73 | AKT2 (0.45) | AKT2AKT1ROCK1ROCK2 | |
| SCHEMBL6532251 | 0.73 | SMN1; SMN2 (0.50) | AKT2AKT1ROCK1MYLK4ROCK2 | |
| SCHEMBL7999525 | 0.73 | AKT2 (0.50) | AKT2AKT1ROCK1MYLK4ROCK2 | |
| SCHEMBL25129902 | 0.73 | TRPA1 (0.46) | AKT2AKT1ROCK1ROCK2TAAR1 | |
| SCHEMBL30290968 | 0.69 | IDO1 (0.45) | AKT2AKT1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |