Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17429931 | 0.97 | DNM1 (0.70) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL10527094 | 0.97 | DNM1 (0.70) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL11365379 | 0.95 | DNM1 (0.67) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL7192483 | 0.95 | DNM1 (0.65) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL11509660 | 0.95 | DNM1 (0.74) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL10524984 | 0.90 | DNM1 (0.83) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL11580967 | 0.90 | DNM1 (0.83) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL22421644 | 0.90 | DNM1 (0.83) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL24508283 | 0.87 | DNM1 (0.79) | DNM1TSHRALDH1A1THRBKDM5A | |
| SCHEMBL20590749 | 0.87 | DNM1 (0.79) | DNM1TSHRALDH1A1THRBKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113736200-A | Antibacterial super absorbent resin composite material and preparation method thereof | 威高集团有限公司 | 2021-12-03 | — | — | CN | disclosed |