Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.69 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GALR3 | O60755 | 1/20 | 0.63 |
| ▸ | BTK | Q06187 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248353 | 0.89 | KMT2A (0.80) | PKMHIF1AEPAS1KMT2AHSD17B10 | |
| SCHEMBL14409556 | 0.86 | SMN1; SMN2 (0.67) | PKMHIF1AEPAS1MAPTTNF | |
| SCHEMBL13747820 | 0.86 | SMN1; SMN2 (0.67) | PKMHIF1AEPAS1MAPTTNF | |
| SCHEMBL14845834 | 0.86 | BTK (0.67) | PKMHIF1AEPAS1MAPTTNF | |
| SCHEMBL28643431 | 0.86 | RAB9A (0.73) | PKMHIF1AEPAS1MAPTTNF | |
| SCHEMBL24024030 | 0.86 | RAB9A (0.73) | PKMHIF1AEPAS1MAPTTNF | |
| SCHEMBL15853659 | 0.85 | HIF1A (0.69) | PKMHIF1AEPAS1KMT2AHSD17B10 | |
| SCHEMBL15651745 | 0.85 | BTK (0.65) | PKMHIF1AEPAS1KMT2AMAPT | |
| SCHEMBL28300862 | 0.85 | BTK (0.68) | HIF1AEPAS1KMT2AHSD17B10MAPT | |
| SCHEMBL878663 | 0.84 | BTK (0.64) | PKMHIF1AEPAS1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623537-B | Synthesis and application of aromatic amine acetylcholinesterase inhibitor containing amine side chain | 中南大学 | 2021-11-12 | — | — | CN | disclosed |