SCHEMBL28670274

SCHEMBL28670274

Cc1cc2c(c(-c3ccccc3)c1C)C=C(c1ccco1)C2[Zr]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 6/20 0.36
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAT2A P31153 2/20 0.33
HPGD P15428 3/20 0.33
SIRT1 Q96EB6 3/20 0.33
CASP1 P29466 1/20 0.33
BLM P54132 1/20 0.33
ALOX5 P09917 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
MAPT P10636 3/20 0.32
TSHR P16473 2/20 0.32
USP2 O75604 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 3/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499657 0.85 PTGS1 (0.40) PTGS1PTGS2ALDH1A1HSD17B10MEN1
SCHEMBL22499738 0.84 CHRM2 (0.34) KMT2A
SCHEMBL22499703 0.83 PTGS1 (0.39) PTGS1PTGS2ALDH1A1HSD17B10MEN1
SCHEMBL22499677 0.83
SCHEMBL22499740 0.81 PTGS1 (0.37) PTGS1PTGS2ALDH1A1HSD17B10MEN1
SCHEMBL22499700 0.79
SCHEMBL22499687 0.79 ALOX5 (0.37) PTGS1PTGS2MEN1KMT2AALOX5
SCHEMBL28884740 0.78 PTGS1 (0.33) PTGS1PTGS2ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL30312740 0.77 ALOX5 (0.34) PTGS1PTGS2ALDH1A1HSD17B10MEN1
SCHEMBL22499671 0.77 PTGS1 (0.34) PTGS1PTGS2MEN1KMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114616280-B Heterophasic propylene ethylene copolymer compositions with desirable balance of mechanical properties 北欧化工公司 2023-10-13 CN disclosed
CN-115702174-A Production of polypropylene with low volatiles 博里利斯股份公司 2023-02-14 CN disclosed
CN-114616280-A Heterophasic propylene ethylene copolymer compositions having a desirable balance of mechanical properties 北欧化工公司 2022-06-10 CN disclosed
CN-113631591-A Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer 日本聚丙烯株式会社 2021-11-09 CN disclosed