Diphenylether

Diphenylether

SCHEMBL28670517

C=CCOP(=O)(O)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 2/20 0.47
GLA P06280 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
SRC P12931 1/20 0.46
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MMP2 P08253 2/20 0.41
CA9 Q16790 2/20 0.41
TGM2 P21980 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LTA4H P09960 3/20 0.41
TSHR P16473 2/20 0.41
S1PR1 P21453 3/20 0.41
PKM P14618 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL23151830 0.98 SMN1; SMN2 (0.46) SMN1; SMN2GAAGLAHTTRAB9A
Phenyl Dihydrogen Phosphate SCHEMBL27908214 0.88 SRC (0.63) SMN1; SMN2SRCCYP2C9CYP2C19TSHR
Phenol SCHEMBL325112 0.84 TSHR (0.43) SMN1; SMN2GLASRCCA9CA14
SCHEMBL11884152 0.84 GAA (0.46) SMN1; SMN2GAAGLAHTTRAB9A
Phenol SCHEMBL15941981 0.83 TSHR (0.42) SMN1; SMN2GLASRCCA9CA14
Phenol SCHEMBL15942098 0.81 TSHR (0.41) SMN1; SMN2GLASRCCA9CA14
SCHEMBL175487 0.79 SRC (0.50) SMN1; SMN2SRCCYP2C9CYP2C19TSHR
SCHEMBL15847030 0.79 LPAR3 (0.50) TDP1
SCHEMBL30321 0.79
SCHEMBL6546158 0.79 ALDH1A1 (0.42) SMN1; SMN2GAAGLAHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801318-A Bishydroxy low molecular weight polyphenylene ether alkyl phosphate, thermosetting resin composition containing the same, and use thereof 兰州瑞朴科技有限公司 2021-12-17 CN disclosed
CN-113801318-A Bishydroxy low molecular weight polyphenylene ether alkyl phosphate, thermosetting resin composition containing the same, and use thereof 兰州瑞朴科技有限公司 2021-12-17 CN disclosed