Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478401 | 1.00 | USP2 (0.35) | USP2SMN1; SMN2GPR119MAPK1CTSK | |
| SCHEMBL16636874 | 1.00 | USP2 (0.35) | USP2SMN1; SMN2GPR119MAPK1CTSK | |
| SCHEMBL28975611 | 0.87 | USP2 (0.34) | USP2SMN1; SMN2MAPK1CTSKNR1H2 | |
| SCHEMBL27824848 | 0.85 | USP2 (0.33) | USP2SMN1; SMN2MAPK1CTSKNR1H2 | |
| SCHEMBL27858888 | 0.85 | USP2 (0.33) | USP2SMN1; SMN2MAPK1CTSKNR1H2 | |
| Ammonia Solution, Strong SCHEMBL22169166 | 0.84 | USP2 (0.33) | USP2SMN1; SMN2MAPK1CTSKEPHX2 | |
| SCHEMBL324691 | 0.83 | USP2 (0.38) | USP2SMN1; SMN2MAPK1CTSKNR1H2 | |
| SCHEMBL3733138 | 0.82 | MAPK1 (0.39) | USP2GPR119MAPK1NR1H2NR1H3 | |
| SCHEMBL25694549 | 0.81 | USP2 (0.37) | USP2SMN1; SMN2MAPK1CTSKNR1H2 | |
| Hydrochloric Acid SCHEMBL18096129 | 0.81 | USP2 (0.37) | USP2SMN1; SMN2MAPK1CTSKNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685514-A | Novel amide pyrrole compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113164771-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |