Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728566 | 0.80 | TSHR (0.60) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL15904504 | 0.80 | LMNA (0.47) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL15904503 | 0.80 | LMNA (0.47) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL225530 | 0.78 | TSHR (0.58) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28518105 | 0.74 | CHRM2 (0.54) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL9117588 | 0.74 | LMNA (0.54) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28522362 | 0.74 | CHRM2 (0.54) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL3373149 | 0.74 | CHRM2 (0.54) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL18283384 | 0.72 | LMNA (0.52) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL29210106 | 0.72 | LMNA (0.52) | LMNATSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-B | 3-tetrazolyl-benzene-1, 2-disulfonamide derivatives as metallo-beta-lactamase inhibitors | 默沙东公司 | 2021-07-13 | — | — | CN | disclosed |