Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189661 | 0.89 | GPR119 (0.58) | USP30GPR119PIK3CDALDH1A1CHEK2 | |
| SCHEMBL6182215 | 0.88 | USP30 (0.53) | USP30GPR119ALDH1A1CHEK2NR1H2 | |
| SCHEMBL12788093 | 0.88 | USP30 (0.53) | USP30GPR119ALDH1A1CHEK2NR1H2 | |
| SCHEMBL3343250 | 0.87 | USP30 (0.52) | USP30GPR119ALDH1A1CHEK2NR1H2 | |
| SCHEMBL14862587 | 0.87 | USP30 (0.52) | USP30GPR119ALDH1A1CHEK2NR1H2 | |
| SCHEMBL16434828 | 0.87 | USP30 (0.52) | USP30GPR119ALDH1A1RORC | |
| SCHEMBL22278158 | 0.87 | USP30 (0.67) | USP30GPR119NAMPTRORC | |
| SCHEMBL15376733 | 0.86 | USP30 (0.54) | USP30GPR119ALDH1A1CHEK2RORC | |
| SCHEMBL74203 | 0.86 | GPR119 (0.67) | USP30GPR119ALDH1A1CHEK2 | |
| SCHEMBL25326842 | 0.85 | USP30 (0.53) | USP30GPR119ALDH1A1CHEK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801094-A | 2-carbonyl benzothiophene compound and preparation method and application thereof | 中国药科大学 | 2021-12-17 | — | — | CN | disclosed |