Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.46 |
| ▸ | MDM4 | O15151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676755 | 0.94 | MDM2 (0.46) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL25360974 | 0.92 | SLC17A5 (0.49) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL31370007 | 0.92 | MDM2 (0.49) | MDM2MDM4TP53ADAM17SLC17A5 | |
| SCHEMBL25360978 | 0.92 | SLC17A5 (0.49) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL31210290 | 0.92 | SLC17A5 (0.49) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL28669758 | 0.91 | MDM4 (0.46) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL31369786 | 0.91 | MDM2 (0.50) | MEN1RECQLKMT2AMDM2MDM4 | |
| SCHEMBL1000833 | 0.91 | ADAM17 (0.51) | MDM2MDM4TP53ADAM17SLC17A5 | |
| SCHEMBL30917941 | 0.91 | ADAM17 (0.51) | MDM2MDM4TP53ADAM17SLC17A5 | |
| SCHEMBL5969202 | 0.91 | ADAM17 (0.51) | MDM2MDM4TP53ADAM17SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861097-A | Synthesis method of multi-configuration 1-Boc-N-Fmoc tryptophan compound | 苏州爱玛特生物科技有限公司 | 2021-12-31 | — | — | CN | disclosed |