Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688274 | 1.00 | MAPT (0.45) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL28669231 | 0.89 | S1PR1 (0.53) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL28929661 | 0.89 | S1PR1 (0.50) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL30688277 | 0.89 | S1PR1 (0.50) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL30688268 | 0.89 | S1PR1 (0.53) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL28674950 | 0.87 | SMN1; SMN2 (0.58) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL30688270 | 0.87 | ADORA3 (0.49) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL30688269 | 0.87 | MAPT (0.45) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL28663179 | 0.87 | MAPT (0.45) | MAPTS1PR1S1PR3NPC1RAB9A | |
| SCHEMBL30688266 | 0.87 | SMN1; SMN2 (0.58) | MAPTS1PR1S1PR3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603684-B | 1,2, 4-oxadiazole Nrf2 activator-tac Lin Pinge product and preparation method and application thereof | 中国药科大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-113603684-A | 1,2, 4-oxadiazole Nrf2 activator-tacrine split product and preparation method and application thereof | 中国药科大学 | 2021-11-05 | — | — | CN | disclosed |