Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634476 | 0.78 | GRIN2D (0.45) | ALDH1A1HPGDKDM4EHSD17B10IDH1 | |
| SCHEMBL16993367 | 0.78 | CHEK1 (0.47) | ALDH1A1HPGDFGFR1HSD17B10MAPT | |
| SCHEMBL30761015 | 0.69 | BRD4 (0.47) | ALDH1A1HPGDLMNADAOKDM4E | |
| SCHEMBL10322137 | 0.67 | DYRK1A (0.43) | ALDH1A1KDM4EMAPT | |
| SCHEMBL16993107 | 0.67 | FGFR1 (0.51) | FGFR1FGFR2FGFR3 | |
| SCHEMBL24665043 | 0.66 | CHEK1 (0.40) | ALDH1A1HPGDLMNAFGFR1KDR | |
| SCHEMBL17119628 | 0.66 | LYN (0.45) | IDH1 | |
| SCHEMBL20331714 | 0.65 | CCNB2 (0.42) | ALDH1A1HPGDLMNAKDM4EHSD17B10 | |
| SCHEMBL9491787 | 0.64 | CYP19A1 (0.68) | ALDH1A1FGFR1KDRDAOTSHR | |
| SCHEMBL14014046 | 0.62 | GRIN2D (0.48) | ALDH1A1HPGDKDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864081-B | FGFR4 inhibitor and preparation and application thereof | 南京圣和药业股份有限公司 | 2021-11-23 | — | — | CN | disclosed |