Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CALM1 | P0DP23 | 4/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891744 | 0.88 | CALM1 (0.75) | CYP19A1CALM1AKR1B1TUBB4ATUBB | |
| SCHEMBL427550 | 0.87 | CYP19A1 (0.55) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL1972535 | 0.86 | CYP19A1 (0.66) | CYP19A1CALM1AKR1B1GABRA1GABRG2 | |
| SCHEMBL153674 | 0.85 | TAAR1 (0.64) | CYP19A1ALDH1A1CALM1AKR1B1TSHR | |
| SCHEMBL9830950 | 0.85 | CYP19A1 (0.59) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL7558508 | 0.85 | CYP19A1 (0.53) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL16453478 | 0.85 | CYP19A1 (0.53) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL6640601 | 0.85 | CYP19A1 (0.53) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL3119714 | 0.85 | CYP19A1 (0.53) | CYP19A1ALDH1A1CALM1AKR1B1DAO | |
| SCHEMBL919408 | 0.85 | AKR1B1 (0.55) | CYP19A1ALDH1A1CALM1AKR1B1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |