Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 13/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | FRK | P42685 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659942 | 0.89 | FLT3 (0.44) | FLT3ADKLCKSRCMAP4K4 | |
| SCHEMBL30569263 | 0.89 | MAP4K4 (0.42) | FLT3ADKLCKSRCMAP4K4 | |
| SCHEMBL30569260 | 0.89 | FLT3 (0.44) | FLT3ADKLCKSRCMAP4K4 | |
| SCHEMBL22418431 | 0.87 | SRC (0.43) | FLT3ADKLCKSRCMAP4K4 | |
| SCHEMBL30441610 | 0.87 | SRC (0.43) | FLT3ADKLCKSRCMAP4K4 | |
| SCHEMBL22418417 | 0.82 | NEK7 (0.51) | FLT3LCKSRCFYNLYN | |
| SCHEMBL28663343 | 0.78 | FLT3 (0.56) | FLT3MAP4K4 | |
| SCHEMBL30569243 | 0.78 | FLT3 (0.56) | FLT3MAP4K4 | |
| SCHEMBL22418461 | 0.76 | FLT3 (0.62) | FLT3LCKSRCMAP4K4FYN | |
| SCHEMBL22418413 | 0.76 | SRC (0.53) | FLT3LCKSRCMAP4K4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |