SCHEMBL30569260 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	FLT3	P36888	14/20	0.44

▸	CYP17A1	P05093	2/20	0.42

▸	MAP4K4	O95819	1/20	0.42

▸	ADK	P55263	1/20	0.42

▸	SRC	P12931	2/20	0.40

▸	LCK	P06239	1/20	0.40

▸	FYN	P06241	1/20	0.40

▸	LYN	P07948	1/20	0.40

▸	HCK	P08631	1/20	0.40

▸	FRK	P42685	1/20	0.40

▸	BLK	P51451	1/20	0.40

▸	PTK6	Q13882	1/20	0.40

▸	EGFR	P00533	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28659942	1.00	FLT3 (0.44)	FLT3CYP17A1MAP4K4ADKSRC
SCHEMBL28671849	0.89	FLT3 (0.45)	FLT3CYP17A1MAP4K4ADKSRC
SCHEMBL30569243	0.89	FLT3 (0.56)	FLT3MAP4K4
SCHEMBL30569263	0.89	MAP4K4 (0.42)	FLT3CYP17A1MAP4K4ADKSRC
SCHEMBL28663343	0.89	FLT3 (0.56)	FLT3MAP4K4
SCHEMBL22418431	0.86	SRC (0.43)	FLT3CYP17A1MAP4K4ADKSRC
SCHEMBL30441610	0.86	SRC (0.43)	FLT3CYP17A1MAP4K4ADKSRC
SCHEMBL22418417	0.81	NEK7 (0.51)	FLT3SRCLCKFYNLYN
SCHEMBL22418413	0.75	SRC (0.53)	FLT3MAP4K4SRCLCKFYN
SCHEMBL30441512	0.75	SRC (0.53)	FLT3MAP4K4SRCLCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-113683629-B	Substituted heteroaryl compounds, compositions and uses thereof	北京范恩柯尔生物科技有限公司	2023-07-04	—	—	CN	disclosed