Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971676 | 0.98 | THRB (0.56) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL11368999 | 0.98 | THRB (0.56) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL2232510 | 0.98 | THRB (0.56) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL9796409 | 0.98 | THRB (0.56) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL23535328 | 0.97 | THRB (0.55) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL28491082 | 0.97 | THRB (0.55) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL972339 | 0.91 | THRB (0.47) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL28131364 | 0.79 | THRB (0.45) | THRBALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL941555 | 0.77 | ESR1 (0.61) | THRBTHRAALDH1A1ESR1ADRA2A | |
| SCHEMBL9505414 | 0.77 | ESR1 (0.61) | THRBTHRAALDH1A1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461382-A | Metal-based catalyst for the production of polydienes | 普利司通美国轮胎运营有限责任公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-113906058-A | Modified high cis polybutadiene polymers, related methods and rubber compositions | 普利司通美国轮胎运营有限责任公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113825777-A | Modified high cis polybutadiene polymers, related methods and tire components | 株式会社普利司通 | 2021-12-21 | — | — | CN | disclosed |