Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673047 | 1.00 | DHODH (0.64) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL19631360 | 0.87 | DHODH (0.78) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL28654546 | 0.86 | DHODH (0.47) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL28654548 | 0.86 | DHODH (0.47) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL25613950 | 0.81 | DHODH (0.61) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL19631366 | 0.78 | DHODH (1.00) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL30131181 | 0.78 | DHODH (1.00) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL20956565 | 0.77 | DHODH (1.00) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL29911563 | 0.77 | DHODH (1.00) | DHODHMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL19631365 | 0.77 | DHODH (1.00) | DHODHMAPTKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773275-B | Antiviral compound and preparation method thereof | 广东中科药物研究有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-113773275-A | Antiviral compound and preparation method thereof | 广东中科药物研究有限公司 | 2021-12-10 | — | — | CN | disclosed |