Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | GUSB | P08236 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654548 | 1.00 | DHODH (0.47) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL28673044 | 0.86 | DHODH (0.64) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL28673047 | 0.86 | DHODH (0.64) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL19631360 | 0.72 | DHODH (0.78) | DHODHMAPTKDM4EALDH1A1POLB | |
| SCHEMBL20956437 | 0.69 | DHODH (0.85) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL19631410 | 0.69 | DHODH (0.85) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL25614522 | 0.69 | DHODH (0.58) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL25614468 | 0.68 | DHODH (0.68) | DHODHGUSBMAPTMEN1KMT2A | |
| SCHEMBL14567100 | 0.66 | PTGS2 (0.63) | GUSBMAPTMEN1KMT2APTGS2 | |
| SCHEMBL15953063 | 0.66 | GUSB (0.60) | DHODHGUSBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773275-B | Antiviral compound and preparation method thereof | 广东中科药物研究有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-113773275-A | Antiviral compound and preparation method thereof | 广东中科药物研究有限公司 | 2021-12-10 | — | — | CN | disclosed |