Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673199 | 1.00 | KLK7 (0.53) | KLK7KLK5PPARAPPARGHDAC8 | |
| SCHEMBL28680370 | 0.90 | F10 (0.48) | KLK7KLK5PPARAPPARGHDAC8 | |
| SCHEMBL8432281 | 0.86 | KLK5 (0.59) | KLK7KLK5PPARAPPARGCTSS | |
| SCHEMBL3007610 | 0.85 | HDAC8 (0.63) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL3007613 | 0.85 | HDAC8 (0.63) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL19359501 | 0.84 | KLK7 (0.56) | KLK7KLK5PPARAPPARGCTSS | |
| SCHEMBL19359503 | 0.84 | KLK7 (0.56) | KLK7KLK5PPARAPPARGCTSS | |
| SCHEMBL3007911 | 0.84 | CYP3A4 (0.49) | HDAC8SYKKDM1AMAOARCOR1 | |
| SCHEMBL3007910 | 0.84 | CYP3A4 (0.49) | HDAC8SYKKDM1AMAOARCOR1 | |
| SCHEMBL14254901 | 0.84 | SIRT2 (0.55) | HDAC8CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943259-A | Amino acid derivative, preparation method and application thereof | 西安禾渼生物医药有限公司 | 2022-01-18 | — | — | CN | disclosed |