Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861278 | 0.93 | SIRT2 (0.53) | CTSSCTSKSIRT1SIRT2HDAC4 | |
| SCHEMBL2698182 | 0.93 | SIRT2 (0.53) | CTSSCTSKSIRT1SIRT2HDAC4 | |
| SCHEMBL28673197 | 0.90 | KLK7 (0.53) | CTSSCTSKSIRT1SIRT2HDAC4 | |
| SCHEMBL28673199 | 0.90 | KLK7 (0.53) | CTSSCTSKSIRT1SIRT2HDAC4 | |
| SCHEMBL20253483 | 0.89 | HDAC8 (0.50) | F10PRSS1CTSSCTSKSIRT1 | |
| SCHEMBL8431546 | 0.87 | PPARA (0.55) | CTSSCTSKPPARAPPARGMEN1 | |
| SCHEMBL8430542 | 0.87 | PPARA (0.55) | CTSSCTSKPPARAPPARGMEN1 | |
| SCHEMBL13359605 | 0.85 | KMT2A (0.54) | F10PRSS1SIRT1SIRT2HDAC4 | |
| SCHEMBL29361609 | 0.85 | SIRT2 (0.58) | CTSKSIRT1SIRT2HDAC4HDAC1 | |
| SCHEMBL14263348 | 0.84 | MEN1 (0.54) | SIRT1SIRT2HDAC8MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943259-A | Amino acid derivative, preparation method and application thereof | 西安禾渼生物医药有限公司 | 2022-01-18 | — | — | CN | disclosed |