Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987029 | 0.86 | SMN1; SMN2 (0.54) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL1106971 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL15549120 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL15549121 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL8580257 | 0.84 | KDM4C (0.66) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8580260 | 0.84 | KDM4C (0.66) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL35210922 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL28684226 | 0.83 | ATM (0.57) | KDM4EALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL27863520 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL38655692 | 0.81 | GAA (0.51) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008053-A | Prodrugs of NMDA receptor modulators | H.隆德贝克有限公司 | 2022-02-01 | — | — | CN | disclosed |